Berberine has a long history of use in traditional Chinese & Ayurvedic medicine where it was used to treat various ailments. In recent years it has risen to natural health stardom due to it’s powerful health promoting benefits.  Science has now caught up with this natural substance from plants and unlocked the potential of it’s use.

Today Berberine is one of the most studied natural compounds and it’s popularity is continuing to grow with over 4500 published studies to date.


What can Berberine be used for?

  • Type 2 diabetes : Berberine is very effective at lowering blood sugar and HbA1c, which are elevated in people with diabetes. It works as well as some pharmaceutical drugs like Metformin / Glucophage.

  • High cholesterol : Studies show that berberine reduces cholesterol and triglyceride levels, while raising HDL (the “good”) cholesterol. It may lower the risk of heart disease in the long-term.

  • Weight loss : Studies have shown that Berberine can cause significant weight loss, while improving all sorts of other health markers at the same time.

  • PCOS  (Polycystic ovarian syndrome) : Research suggests that berberine can lower blood sugar, improve cholesterol & triglyceride levels, reduce testosterone levels, and lower waist-to-hip ratio in women with PCOS.




Did You Know? 

Some research shows that berberine can lower blood sugar levels similar to metformin, but berberine seems to improve cholesterol levels better than metformin.
Berberine has a half-life of several hours, so it is better to spread your dosage to several times per day to achieve stable blood levels.


How does it work ?

Berberine has multiple actions but the primary one is it’s ability to activate AMP-activated protein kinase (AMPK).
AMPK inhibition is directly linked to metabolic syndrome which is characterized by high cholesterol, high glucose / sugar levels, high blood pressure and excess body fat.
Clinical studies have shown that Berberine and Metformin share a similar potency for AMPK activation and are amongst a handful of substances known to have such an effect.

Taking berberine has been shown to help with improving a range of many conditions, with benefits like the following:

  • Improves insulin resistance
  • Lowers testosterone
  • Reduces acne
  • Lowers cholesterol levels
  • Improves non-alcoholic fatty liver disease
  • Improves fertility
  • Offers anti-microbial benefits
  • Lowers high blood pressure
  • Aids in weight loss and body fat loss

Berberine can offer numerous benefits to women with PCOS including improving fertility, assisting with weight loss, and lowering the risk of metabolic complications that are associated with the syndrome such as type 2 diabetes, high cholesterol, and fatty liver disease.

If you have a medical condition or are on any medications, then it is recommended that you speak to your doctor before taking Berberine. Not recommended for use during pregnancy and breastfeeding.



Coyne Healthcare Bio-Berberine complex benefits include:

  • High potency 100% pure berberine extract with Green Tea and Chromium for added benefits

  • Free from artificial additives, gluten, sugar and preservatives

  • GMO free

  • Vegetarian-friendly